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The original idea that set DS apart from most other games was that your initial choice of character did not lock you in. You could develop the same skills, reach the same levels in anything you chose, by just using the skill you wanted to increase.

If you have equipment based on the initial choice of race or gender, which you can't develop in a new direction, then you've got a different game. Yes, it's possible, but it's turning DS into the other type of game. Which may be a reasonable approach for a Total Conversion project.

Having a vendor stock both male and female versions of some item would be a different situation, but unless they always drop in pairs, too, it just increases the proportion of items you can't use, because it has requirements you don't meet.