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I didn't use the npc icons, don't like them. I was aiming for immersion in the map, hope this isn't too big of an incovenience.
There are six vendors and one enchanter at the traders caravan.
If you take the Ellennu lift, there is a Pet shop. Down by the Falls, Reagent sales.
One vendor, Bosbie the blacksmith, and one enchanter in Skye.
Captain Kirk is out in the boonies, West of Skye.
The Sargent at Winhaven has supplies, once you have retaken Windhaven from the Northern Celts.
In Eastport there are four vendors and one reagent salesman. The vendors in Eastport are, the Blacksmith, Malchom, easy to find, Angus, standing in front of his shop, Elvira the Herbalist, in the garden, and Derown, on the top floor of the Archives. Arcanist Agrand is sitting at a table at the rear of his home.

All vendors have the same "Super Store" supplies, they carry everything, weapons, armor, potions, reagents, etc.

There are two innkeepers where you can find your party members, one in Skye and one in Eastport. The Skye innkeeper is quite often in the backrooms. In Eastport, look on the top floor of the Stone Maiden Inn.

Insofar as Quests go, they are all over the map. Immediately on leaving Ellennu, you will run in to quests, especially heading East. A quest triggers when you approach the Ellennu Teleporter.

In Skye you will find the only secondary quest. Talk to Garth.